As of May 25th, 2023, 766 million COVID-19 cases and over 6.9 million deaths worldwide had been reported to the World Health Organization.[1] In the pursuit of combating this global crisis, innovative approaches like reverse vaccinology offer a ray of hope for developing effective vaccines against COVID-19.[2] [3] These advancements not only address the urgent demands of the pandemic but also pave the way for proactive and resilient responses to future infection threats. Whilst current COVID-19 treatment primarily relies on supportive care, monoclonal antibodies or non-specific medications, the persistently high mortality rate among vulnerable populations underscores the critical need for therapeutic alternatives.[4] [5] By embracing the principles of integrative medicine, including homeopathy, continued research and exploration of novel therapeutic strategies are vital in our collective battle against COVID-19 and the prevention of future epidemics.[6] [7]