Methods: This study considered 81 patients with CKD and investigated the correlation between the disease and the patients' demographics, anamnesis, and clinical presentation, as well as the potential relationship between the disease and other illnesses.Results: A signifiant number of diseases can lead to the manifestation of CKD, and notably, many of them are idiopathic. However, despite the rapid development in medical science and pharmaceutical technology and a plethora of research trials, there is a lack of ability to identify and analyze the causes and pathophysiologic mechanisms that are responsible for the manifestation of CKD.Conclusions: This retrospective study investigates the factors that may play a role in the manifestation of CKD through the knowledge and research of both conventional medicine and homeopathy.