Fahimeh Mousavi, Yalda Nozad Mojaver, Mehdi Asadzadeh and Mustafa Mirzazadeh
Homeopathic treatment of minor aphthous ulcer: a randomized, placebo-controlled clinical trial
Homeopathy, 2009, 98 (3), 137-141
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Objective - The objectives of this study were to clinically determine the efficacy of individualised homeopathy in the treatment of minor recurrent aphthous ulceration (MiRAU).Design & intervention - A randomized, single blind, placebo-controlled clinical trial of individualised homeopathy. One hundred patients with minor aphthous ulcer were treated with individualised homeopathic medicines or placebo and followed up for 6 days. Patients received two doses of individualised homeopathic medicines in the 6C potency as oral liquid at baseline and 12 h later. Pain intensity and ulcer size were recorded at baseline during and at the end of the trial (mornings of days 4 and 6).Result - All 100 patients completed treatment. Between group differences for pain intensity and ulcer size were statistically significant at day 4 and at day 6 (P < 0.05). No adverse effects were reported.Conclusion - The results suggest that homeopathic treatment is an effective and safe method in the treatment of MiRAU.